Microstructure and antibacterial performance of functionalized polyurethane based on polysiloxane tethered cationic biocides
Microstructure and antibacterial performance of functionalized polyurethane based on polysiloxane tethered cationic biocides
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聚硅氧烷系链阳离子杀菌剂功能化聚氨酯的微观结构及抗菌性能
DOI：
10.1039/c5ra12945a
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发表时间：
2015
期刊：
影响因子：
3.9
通讯作者：
Tang Hao
中科院分区：
文献类型：
--
作者：
Zhang Qinghua;Liu Hailong;Zhan Xiaoli;Chen Fengqiu;Yan Jie;Tang Hao
设计了一种基于聚硅氧烷系链阳离子杀菌剂的多功能聚氨酯，以达到抗污染和抗菌的目的。通过水解缩聚和季铵化反应合成了不同组成的季铵盐官能化端羟基聚硅氧烷（PQMS）。以PQMS和PPG为软段，采用两步缩聚法合成了一系列抗菌聚氨酯共聚物（PQMS-PU）。采用GPC、FTIR、1H-NMR等分析手段对其化学结构和组成进行了表征。用XPS定量表征了聚硅氧烷链段上的QAS基团的表面迁移和N+在表面的分布。通过AFM、TEM和动态接触角测试研究了共聚物膜的微相形态和润湿性能。测定了由聚硅氧烷软段和硬段之间的微相分离引起的杀生物剂基团向表面的迁移。研究了聚硅氧烷链段和QAS基团在共聚物表面的分布与共聚物膜的润湿性和抗菌活性之间的定量关系。在设计范围内，所得共聚物具有很低的表面自由能和对大肠杆菌的优良抗菌活性，这对纺织品和船舶涂料具有重要的环保意义和工业价值。
Multifunctional polyurethane based on polysiloxane tethered cationic biocides was designed for fouling resistance and antibacterial objectives. Quaternary ammonium salt (QAS) functionalized hydroxy-terminated polysiloxanes (PQMS) with different compositions were synthesized by hydrolytic polycondensation and subsequent quaternization. Then, a series of antibacterial polyurethane copolymers (PQMS–PU) with PQMS and PPG as soft segments were prepared by two-step condensation methods. GPC, FTIR and 1H-NMR were employed to analyze the chemical structural and composition. The surface migrations of polysiloxane segment tethered QAS groups and the distribution of N+ on the surface were quantitatively characterized by XPS. The microphase morphology and wettability properties of the copolymer films were investigated by AFM, TEM and dynamic contact angle tests. The migration of the biocide groups to the surface caused by the microphase separation between polysiloxane soft segments and hard segments was determined. The quantitative relationships of the polysiloxane segments and QAS group distribution on the surface with the wettability and antibacterial activity of the copolymer films were demonstrated. Within the designed range, the obtained copolymers exhibited very low surface free energy and excellent antibacterial activity towards Escherichia coli, which was of great environmental friendliness and industrial interest for textile and marine coating application.