OpenVax: An Open-Source Computational Pipeline for Cancer Neoantigen Prediction
OpenVax: An Open-Source Computational Pipeline for Cancer Neoantigen Prediction
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DOI:
10.1007/978-1-0716-0327-7_10
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发表时间:
2020-01-01
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影响因子:
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通讯作者:
Rubinsteyn, Alex
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文献类型:
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作者:
Kodysh, Julia;Rubinsteyn, Alex
OpenVax is a computational workflow for identifying somatic variants, predicting neoantigens, and selecting the contents of personalized cancer vaccines. It is a Dockerized end-to-end pipeline that takes as input raw tumor/normal sequencing data. It is currently used in three clinical trials (NCT02721043, NCT03223103, and NCT03359239). In this chapter, we describe how to install and use OpenVax, as well as how to interpret the generated results.