Adenovirus vectors activate Vd2+ ?dT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
Adenovirus vectors activate Vd2+ ?dT cells in a type I interferon-, TNF-, and IL-18-dependent manner.
复制标题
腺病毒载体以I型干扰素、TNF和IL-18依赖性方式激活Vd2ΔdT细胞。
DOI：
10.1002/eji.202149367
复制
发表时间：
2022
影响因子：
5.4
通讯作者：
Provine NM
中科院分区：
文献类型：
--
作者：
Provine NM
Vδ2+ γδT cells are unconventional T cells that can be activated by cytokines without TCR signaling. Adenovirus vaccine vectors activated Vδ2+ γδT cells in an interleukin 18-, TNF-, and type I interferon-dependent manner. This stimulatory capacity was associated with adenovirus vectors of non-species C origin, including the ChAdOx1 vaccine platform.
