Time Courses of Intrapartum Asphyxia: Neonatal Characteristics and Outcomes
Time Courses of Intrapartum Asphyxia: Neonatal Characteristics and Outcomes
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DOI：
10.1055/s-0028-1095185
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发表时间：
2009-01-01
影响因子：
2
通讯作者：
Perlman, Max
中科院分区：
文献类型：
--
作者：
Shah, Prakesh S.;Perlman, Max
我们比较了缺氧缺血性脑病新生儿的新生儿特征和不良转归率，包括：(1)长时间部分窒息，(2)急性产时近全窒息，以及(3)两者合并。侮辱的时间过程由两位作者根据产科数据和新生儿图表分别确定。“严重不良后果”定义为2岁时可检测到的死亡或严重残疾。窒息时间过程为延长部分窒息167例（45%），急性接近完全窒息96例（26%），合并窒息78例（21%），不确定34例（8%）。在已知病程和结局的患者中，212例（67%）有严重不良反应，103例（33%）无严重不良反应。严重不良结局发生率为：延长部分窒息61%，急性接近完全窒息67%，合并时间过程窒息79% （p=0.025）。长期结果根据侮辱的时间进程而不同；合并时间疗程的婴儿结果最差。
We compared neonatal characteristics and adverse outcome rates of neonates with hypoxic-ischemic encephalopathy following (1) prolonged partial asphyxia, (2) acute near-total intrapartum asphyxia, and (3) the two combined. The time course of the insult was determined individually by two authors from obstetric data and neonatal charts. "Severe adverse outcome" was defined as death or severe disability detectable by age 2 years. The asphyxial time course was prolonged partial asphyxia in 167 (45%), acute near-total asphyxia in 96 (26%), combined in 78 (21%), and indeterminate in 34 (8%) patients. Among patients with known time course and outcomes, 212 (67%) had severe adverse outcome and 103 (33%) were free of severe adverse outcome. Severe adverse outcome rates were 61% for prolonged partial asphyxia, 67% for acute near-total asphyxia, and 79% for combined time course asphyxia (p=0.025). Long-term outcomes differ according to the time course of the insult; infants with combined time course had the worst outcome.