Efficacy of tribromoethanol anesthesia in mice.
Efficacy of tribromoethanol anesthesia in mice.
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发表时间：
1993-04
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通讯作者：
V. Papaioannou;Fox Jg
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作者：
V. Papaioannou;Fox Jg
我们进行了一项回顾性研究，以评估三溴乙醇（0.2 ml/ 10g体重的1.2%溶液）作为小鼠手术麻醉剂的有效性、安全性和适用性。我们收集了2.5年期间（1989-1991）的胚胎移植记录，并对需要麻醉的小鼠进行了检查。我们记录了低死亡率和发病率（< 1%），没有任何明显的腹部粘连或炎症反应。快速的诱导和恢复，足够的麻醉手术平面，以及缺乏并发症，使这种麻醉剂有效且使用简单。防止麻醉剂分解的必要预防措施，在4摄氏度的黑暗中储存，是最小的。
We undertook a retrospective study to evaluate the efficacy, safety, and suitability of tribromoethanol (0.2 ml/10 g body weight of a 1.2% solution) as a surgical anesthetic in mice. We compiled records of embryo transfer during a 2.5-year period (1989-1991) and examined mice subjected to several other procedures requiring anesthesia. We documented a low rate of mortality and morbidity (< 1%) and the absence of any significant abdominal adhesions or inflammatory response. The rapid induction and recovery, adequate surgical plane of anesthesia, and lack of complications make this anesthetic effective and simple to use. Precautions necessary to prevent decomposition of the anesthetic, storage in the dark at 4 degrees C, were minimal.