A CHITIN-BINDING LECTIN FROM STINGING NETTLE RHIZOMES WITH ANTIFUNGAL PROPERTIES
A CHITIN-BINDING LECTIN FROM STINGING NETTLE RHIZOMES WITH ANTIFUNGAL PROPERTIES
复制标题
DOI：
10.1126/science.245.4922.1100
复制
发表时间：
1989-09-08
期刊：
影响因子：
56.9
通讯作者：
PEUMANS, WJ
中科院分区：
文献类型：
--
作者：
BROEKAERT, WF;VANPARIJS, J;PEUMANS, WJ
刺荨麻的根茎含有一种小尺寸的凝集素，对几丁质具有结合特异性。这种凝集素在体外抑制几种植物病原性和腐殖性含几丁质真菌的生长。荨麻凝集素的抗真菌作用不同于几丁质酶的作用，几丁质酶是一类普遍存在的抗真菌植物蛋白。此外，荨麻凝集素与几丁质酶在抑制真菌生长方面具有协同作用。荨麻凝集素在抗病作物基因工程中具有潜在的应用前景。
Rhizomes of stinging nettle contain a small-sized lectin that exhibits binding specificity toward chitin. This lectin inhibits growth of several phytopathogenic and saprophytic chitin-containing fungi in vitro. The antifungal action of the nettle lectin differs from the action of chitinases, which are a ubiquitous class of antifungal plant proteins. Moreover, the nettle lectin acts synergistically with chitinase in inhibiting fungal growth. The nettle lectin may be a promising candidate for possible applications in the genetic engineering of disease-resistant crops.