Real-time SPARSE-SENSE cine MR imaging in atrial fibrillation: a feasibility study

Real-time SPARSE-SENSE cine MR imaging in atrial fibrillation: a feasibility study
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DOI:
10.1177/0284185116681037
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发表时间:
2017-08-01
期刊:
影响因子:
1.3
通讯作者:
Nassenstein, Kai
Nassenstein, Kai
中科院分区:
医学4区
文献类型:
--
作者:
Goebel, Juliane;Nensa, Felix;Nassenstein, Kai

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背景:心脏磁共振成像(MRI)依赖于正确的心电图门控,这在心律失常时受到阻碍。目的:探讨基于稀疏感知(SPARSE - sense)的自由呼吸实时影像序列原型是否能改善心房颤动左室量化。材料与方法:在1.5T MR系统上获得20例伴有心律失常排斥反应的房颤患者的左室稀疏序列和参考稳态自由进动(SSFP)序列的短轴叠加。两名放射科医生使用4分制独立评定了两组序列中心律失常引起的伪影严重程度。获得了两个序列心肌信号强度的变异系数。容量测定由一名读取器进行两次,另一名读取器进行一次。采用修正Fisher精确检验分析伪迹严重程度与使用序列的相关性。变异系数和体积数据采用配对t检验和类内相关性进行比较。结果:在SSFP的两种阅读器中,心律失常引起的伪影严重程度中位数为2,在稀疏阅读器中为0(阅读器1)/1(阅读器2),在稀疏阅读器中显著低于(P
Background: Cardiac magnetic resonance imaging (MRI) relies on correct ECG-gating, which is hindered in arrhythmia.Purpose: To examine whether a prototype free-breathing real-time cine sequence using SPARSE-SENSE (SPARSE) improves left ventricular quantification in atrial fibrillation.Material and Methods: On a 1.5T MR system left ventricular short-axis stacks were acquired of the SPARSE sequence and of a reference steady-state free precession (SSFP) sequence with arrhythmia rejection in 20 patients with atrial fibrillation. Two radiologists independently rated arrhythmia-caused artifact severity in both sequences using a 4-point scale. Coefficients of variation of myocardial signal intensity for both sequences were acquired. Volumetry was performed twice by one reader and once by another reader. Correlation between artifact severity and employed sequence was analyzed by modified Fisher's exact test. Coefficients of variation and volumetric data were compared by paired t-test and intraclass correlation.Results: Median arrhythmia-caused artifact severity was 2 in both readers for SSFP and 0 (reader 1)/1 (reader 2) for SPARSE, being significantly lower in SPARSE (P