The role of allergy in oral mucosal diseases
The role of allergy in oral mucosal diseases
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DOI：
10.1093/qjmed/93.8.507
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发表时间：
2000-08-01
期刊：
影响因子：
--
通讯作者：
Forsyth, A
中科院分区：
文献类型：
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作者：
Wray, D;Rees, SR;Forsyth, A
我们回顾性评估了 1252 名就诊于格拉斯哥牙科医院和学校口腔科并转诊至格拉斯哥皇家医院接触性皮炎调查科的口腔粘膜疾病患者的皮肤斑贴试验阳性结果的发生率，以及在疾病过程中排除已识别过敏原的相关性。将每个疾病队列的斑贴试验阳性率与 100 名对照志愿者进行比较。与对照组相比，患有口腔粘膜疾病的患者更有可能对食品添加剂（尤其是苯甲酸）以及香水和调味品（尤其是肉桂醛）产生明显的过敏反应，并且回避疗法使大多数患者得到改善。斑贴测试和由此产生的回避疗法是口腔粘膜疾病治疗的有用辅助手段。
We retrospectively assessed the prevalence of positive results to cutaneous patch testing, and the relevance of exclusion of identified allergens in the disease process, in 1252 patients with oral mucosal diseases presenting to the Department of Oral Medicine in Glasgow Dental Hospital and School and referred to the Contact Dermatitis Investigation Unit in Glasgow Royal Infirmary. The prevalence of patch-test positivity in each disease cohort was compared with that in 100 control volunteers. Patients with oral mucosal diseases were significantly more likely to have demonstrable hypersensitivity to food additives, especially benzoic acid, and perfumes and flavourings, especially cinnamaldehyde, than controls, and avoidance therapy caused improvement in the majority. Patch testing and the resultant avoidance therapy are useful adjuncts in the management of oral mucosal diseases.