PREVALENCE OF PSYCHIATRIC-DISORDERS IN EARLY STAGES OF HIV-INFECTION
PREVALENCE OF PSYCHIATRIC-DISORDERS IN EARLY STAGES OF HIV-INFECTION
复制标题
DOI：
10.1097/00006842-199209000-00006
复制
发表时间：
1992-09-01
影响因子：
3.3
通讯作者：
TEMOSHOK, L
中科院分区：
文献类型：
--
作者：
BROWN, GR;RUNDELL, JR;TEMOSHOK, L
作为军队普遍艾滋病毒筛查计划的一部分，442名男性在通知艾滋病毒血清转化后，评估了DSM-III-R定义的精神疾病和焦虑和抑郁症状的存在。其中，84.4%的人在接受采访时处于疾病的最早期、无症状阶段（96%没有艾滋病）。采用DSM-III-R结构化临床访谈和汉密尔顿焦虑抑郁量表结构化访谈指南。相关的比较流行病学集水区患病率数据。在社区中，艾滋病毒血清反应阳性的男子比年龄匹配的男子更有可能目前被诊断为严重抑郁症（18-44岁）和焦虑症（25-44岁）。终生抑郁症和酒精使用障碍的发生率较高，目前性功能障碍的患病率较高（21.7%）。我们的结论是，艾滋病毒血清阳性的男性在得知血清转换之前，情绪和物质使用障碍的发生率很高，并且在艾滋病毒感染过程的早期，男性有患上严重抑郁症、焦虑症和性欲障碍的风险。
As part of a military universal HIV screening program, 442 men were assessed for the presence of DSM-III-R defined psychiatric disorders and symptoms of anxiety and depression after notification of HIV seroconversion. Of them, 84.4% were in the earliest, asymptomatic stages of disease at the time of interview (96% did not have AIDS). The Structured Clinical Interview for DSM-III-R and Structured Interview Guide for the Hamilton Anxiety and Depression Scales were used. Relevant comparisons were made to Epidemiologic Catchment Area prevalence data. HIV seropositive men were more likely than age-matched men in the community to have current diagnoses of major depression (ages 18-44) and anxiety disorders (ages 25-44). Higher lifetime rates of major depression and alcohol use disorder, and high current prevalence of sexual dysfunction (21.7%) were noted. We conclude that men who become HIV seropositive have high rates of mood and substance use disorders prior to knowledge of seroconversion, and that early in the course of HIV infection men are at risk for developing major depression, anxiety disorders, and disorders of sexual desire.