Osmotic shock induces the presence of glycocardiolipin in the purple membrane of Halobacterium salinarum Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300212-JLR200
Osmotic shock induces the presence of glycocardiolipin in the purple membrane of Halobacterium salinarum Published, JLR Papers in Press, August 16, 2003. DOI 10.1194/jlr.M300212-JLR200
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渗透压休克诱导盐杆菌紫色膜中存在糖心磷脂已出版，JLR 论文出版，2003 年 8 月 16 日。DOI 10.1194/jlr.M300212-JLR200
DOI：
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发表时间：
2003
影响因子：
6.5
通讯作者：
A. Corcelli
中科院分区：
文献类型：
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作者：
S. Lobasso;P. Lopalco;V. Lattanzio;A. Corcelli
在盐生盐杆菌的紫膜(PM)中，含有一种由磺基三糖基二醚(S-TGD-1)酯化而成的磷脂二聚体，即S-TGD-1-PA，称为心磷脂(Glyc)(Corcell，A.，M.Colella，G.Mascolo，F.P.Fanizzi和M.Kates)。紫膜中一种新的糖脂和磷脂。2000年。生物化学。39：3318-3326)。分析了盐藻全细胞、质膜和其他细胞组分的糖类含量。甘露糖是盐藻细胞中一种不丰富的磷脂，是分离的质膜的主要磷脂之一。在本报告中，我们证明了a)甘氨酸是在PM的分离过程中形成的，b)渗透压休克特异性地诱导了盐碱蓬细胞中葡萄糖的升高，c)与血糖的升高相对应，S-TGd-1的水平也发生了下降。在PM分离过程中观察到的膜脂组成的变化是由于S-TGD-1从头合成甘露糖所致。
In the purple membrane (PM) of Halobacterium salinarum is present a phospholipid dimer consisting of sulfo-triglycosyl-diether (S-TGD-1) esterified to the phosphate group of phosphatidic acid (PA), i.e., S-TGD-1-PA, called glycocardiolipin (GlyC) (Corcelli, A., M. Colella, G. Mascolo, F. P. Fanizzi, and M. Kates. A novel glycolipid and phospholipid in the purple membrane. 2000. Biochemistry. 39: 3318–3326). The GlyC content of whole cells, PM, and other cell fractions of H. salinarum have been analyzed. GlyC is a nonabundant phospholipid in H. salinarum cells, and it represents one of the major phospholipids of isolated PM. In this report, we show that a) GlyC is formed during the isolation of PM, b) GlyC increase in H. salinarum cells is specifically induced by osmotic shock, and c) in correspondence with GlyC increase, a decrease of S-TGD-1 levels occurs. The changes in membrane lipid composition observed during the isolation of PM are due to de novo synthesis of GlyC from S-TGD-1.
保护游离羟基的心磷脂衍生物的合成：其在心磷脂刺激细胞色素c氧化酶的研究中的应用。
影响因子：
2.9
作者：
Dale,MP;Robinson,NC
通讯作者：
Robinson,NC