Drug-Resistant Malaria: The Era of ACT.
Drug-Resistant Malaria: The Era of ACT.
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DOI：
10.1007/s11908-010-0099-y
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发表时间：
2010-05
影响因子：
3.1
通讯作者：
Wongsrichanalai, Chansuda
中科院分区：
文献类型：
--
作者：
Lin, Jessica T;Juliano, Jonathan J;Wongsrichanalai, Chansuda
随着抗药性恶性疟疾在全球范围内不断发展和蔓延，青蒿素类联合疗法已成为过去十年全球疟疾控制的核心。本综述讨论了如何在抗疟药物耐药性监测和合理使用现有的一系列青蒿素综合疗法方面取得进展，以最大限度地发挥这一高效疗法的影响，即使东南亚正在出现青蒿素耐药性。
As drug-resistant falciparum malaria has continued to evolve and spread worldwide, artemisinin-based combination therapies (ACT) have become the centerpiece of global malaria control over the past decade. This review discusses how advances in antimalarial drug resistance monitoring and rational use of the array of ACTs now available can maximize the impact of this highly efficacious therapy, even as resistance to artemisinins is emerging in Southeast Asia.