Physical model-based indirect measurements of blood pressure and flow using a centrifugal pump.

Physical model-based indirect measurements of blood pressure and flow using a centrifugal pump.
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使用离心泵基于物理模型间接测量血压和流量。

DOI:
10.1046/j.1525-1594.2000.06605.x
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发表时间:
2000
期刊:
影响因子:
2.4
通讯作者:
C. Nojiri
C. Nojiri
中科院分区:
工程技术3区
文献类型:
--
作者:
T. Kitamura;Y. Matsushima;T. Tokuyama;S. Kono;K. Nishimura;M. Komeda;M. Yanai;T. Kijima;C. Nojiri

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本文介绍了一种间接测量泵压差和流量的技术,具有一定的精度,独立于血液粘度的变化。该技术基于使用离心泵系统的物理模型方程的电机电流和转速的非侵入性测量。首先估计包括在动态方程的系数中的血液粘度,然后将估计的粘度代入模型的稳态方程中,提供泵流量和压差。使用Capiox泵进行的体外试验显示,压差和泵流量的实际值与其估计值之间存在充分的线性相关性。使用45公斤的羊在体内的测试表明,所提出的算法需要的粘度估计的收敛鲁棒性。然而,开发的算法/模型的总体评价表明,在有效的计算和建模方面取得了成功。
This article describes a technique offering indirect measurements of pump pressure differential and flow with certain accuracy independent of changes in blood viscosity. This technique is based on noninvasive measurements of the motor current and rotation speed using the physical model equations of the centrifugal pump system. Blood viscosity included in the coefficients of the dynamic equations is first estimated, and then substitution of the estimated viscosity into the steady equations of the model provides pump flow and pressure differential. In vitro tests using a Capiox pump showed a sufficient linear correlation between actual values and their estimates for pressure differential and pump flow. An in vivo test using a 45 kg sheep showed that the proposed algorithm needs robustness for the convergence of estimates of viscosity. An overall evaluation, however, of the developed algorithm/model showed indications of success in terms of efficient computation and modeling.