Analyte migration electrospray ionization for rapid analysis of complex samples with small volume using mass spectrometry.
Analyte migration electrospray ionization for rapid analysis of complex samples with small volume using mass spectrometry.
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DOI：
10.1039/c4an01397b
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发表时间：
2014-10
期刊：
影响因子：
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通讯作者：
Qian Wang;Hanbin Zhong;Yajun Zheng;Sichun Zhang;Xiaoning Liu;Xinrong Zhang;Xiaoling Zhang;Zhiping Zhang
中科院分区：
文献类型：
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作者：
Qian Wang;Hanbin Zhong;Yajun Zheng;Sichun Zhang;Xiaoning Liu;Xinrong Zhang;Xiaoling Zhang;Zhiping Zhang
复杂的生物基质由于在有机溶剂中的溶解度较弱，因此可以在分析物迁移过程中有效去除。该技术还具有其他潜在优势，包括高灵敏度以及无需任何预处理即可直接分析小体积原始样品中的成分及其代谢物的能力。
Complex biological matrices can be effectively removed in the analyte migration process because of their weak solubility in organic solvents. This technique offers other potential advantages, including high-sensitivity and the capability of performing a direct analysis of the components and their metabolites in small-volume raw samples without any pretreatment.