African American ESRD patients have a high pre-dialysis prevalence of kidney stones compared to NHANES III
African American ESRD patients have a high pre-dialysis prevalence of kidney stones compared to NHANES III
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DOI：
10.1007/s00240-007-0079-3
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发表时间：
2007-04-01
影响因子：
--
通讯作者：
Worcester, Elaine
中科院分区：
文献类型：
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作者：
Stankus, Nicole;Hammes, Mary;Worcester, Elaine
如果肾结石（NL）促进进展为终末期肾病（ESRD），需要肾脏替代治疗，则可以预期ESRD受试者中ESRD前结石的患病率高于非ESRD受试者。我们比较了非洲裔美国人（AA）血液透析（HD）人群中ESRD前结石的患病率与第三次全国健康与营养调查（NHANES III）获得的全国代表性AA人群中估计的结石患病率。对在芝加哥大学接受透析治疗的300例AA HD患者进行面对面问卷调查，以确定ESRD前NL患病率。所有关于ESRD前结石患病率的数据均通过记录的病史、放射学和实验室检查结果（如可用）进行证实。AA HD患者中ESRD前NL的患病率为8.3%，而在年龄、种族和性别校正的NHANES III人群中为2.8%（P < 0.001）。校正年龄和性别后，估计AA HD患者中ESRD前肾结石的患病率显著高于一般AA人群中发现的肾结石患病率。
If nephrolithiasis (NL) promotes progression to end stage renal disease (ESRD), requiring renal replacement therapy, one might expect a higher prevalence of pre-ESRD stones among ESRD versus non-ESRD subjects. We compared the prevalence of pre-ESRD stones in an African-American (AA) hemodialysis (HD) population to the estimated stone prevalence in a nationally representative cohort of AA persons as obtained by the Third National Health and Nutrition Survey (NHANES III). Face-to-face questionnaires were administered to a sample of 300 AA HD patients undergoing dialysis therapy at the University of Chicago to determine pre-ESRD NL prevalence. All data on pre-ESRD stone prevalence was confirmed by documented medical history, radiology and laboratory findings, where available. Prevalence of pre-ESRD NL in AA HD patients was 8.3% versus 2.8% in the age, race and sex adjusted NHANES III population (P < 0.001). After adjustment for age and sex, it was estimated that the prevalence of pre-ESRD kidney stones among AA HD patients is significantly higher than the prevalence of kidney stones found in the general AA population.