The Interferon System
The Interferon System
复制标题
干扰素系统
DOI：
10.1007/978-3-7091-3432-0
复制
发表时间：
1979
期刊：
影响因子：
--
通讯作者：
W. E. Stewart
中科院分区：
文献类型：
--
作者：
W. E. Stewart
这本书是干扰素的更新，由Jan Vilcek博士于1969年出版。干扰素的研究领域已经从以前的严格将干扰素作为抗病毒物质的狭窄治疗扩展，使得干扰素系统现在包括从免疫改变到细胞增殖限制再到抗肿瘤活性的细胞调节。干扰素的这些非抗病毒功能的数量稳步增加，强调了对干扰素研究的整个文献进行全面和批判性综述的必要性。正文，与它的支持书目，提供干扰素研究的完全覆盖。一个新来的人应该在这里找到所有必要的信息来理解为什么干扰素，已经研究了二十多年，最初激起了对它的临床前景的兴奋，仍然激发了对这种潜力的猜测。对于那些已经熟悉了干扰素似乎永久的临床承诺，这卷应该作为一个有价值的参考来源，关于这个问题的最大的书目曾经出现在一个封面。显然，这本书应该被认为只是作为一个介绍的主题，并作为一个参考来源;大多数问题的干扰素系统仍然没有答案，甚至没有问。希望对迄今为止所做工作的总结和批判性评价将激励和促进进一步的进展。
This book is an update of Interferon, published in 1969 by Dr. Jan Vilcek. The field of interferon research has since expanded from its former narrow treatment of interferon strictly as an antiviral substance, such that The Interferon System now encompasses cellular modulations ranging from immune alterations to cell proliferative restrictions to antitumor activities. The steadily increasing number of these non-antiviral functions of interferons emphasizes the need for a comprehensive-and critical-review of the entire literature of interferon studies. The text, with its supporting bibliography, provides complete coverage of interferon research. A newcomer to the area should find here all the informa tion necessary to understand why interferon, which has been studied for more than twenty years and which originally stirred excitement over its clinical pros pects, is still inspiring speculation about this potential. For those already fa miliar with the seemingly perpetual clinical promise of interferon, this volume should serve as a valuable reference source, the largest bibliography on the subject ever to appear under one cover. Clearly, this book should be considered only as an introduction to the topic and as a reference source; most questions about the interferon system are still unanswered-even unasked. Hopefully this summation and critical evalua tion of work done to date will stimulate and facilitate further progress.