LYSOSOMAL ENZYME-RELEASE DURING CARDIOPULMONARY BYPASS
LYSOSOMAL ENZYME-RELEASE DURING CARDIOPULMONARY BYPASS
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DOI：
10.1111/j.1365-2044.1977.tb10074.x
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发表时间：
1977-01-01
期刊：
影响因子：
10.7
通讯作者：
WELMAN, E
中科院分区：
文献类型：
--
作者：
GNANADURAI, TV;BRANTHWAITE, MA;WELMAN, E
溶酶体酶的释放发生在人的心肺转流过程中，但这些酶来源的组织尚未确定。血浆中N-乙酰β-氨基葡萄糖苷酶的活性增加到与转流持续时间成比例的程度，因此该酶可能是心肺转流引起的组织损伤的比β-葡萄糖醛酸酶更好的标志物，与仅手术引起的组织损伤不同。
Lysosomal enzyme release occurs during cardiopulmonary bypass in man but the tissues from which these enzymes originate have not been identified. The activity of N-acetyl beta-glucosaminidase in plasma increases to a degree which is proportional to the duration of bypass and this enzyme may therefore be a better marker than beta-glucuronidase of tissue damage caused by cardiopulmonary bypass, as distinct from tissue damage solely to the operative procedure.