LIGHT-MICROSCOPE BASED ANALYSIS OF 3-DIMENSIONAL STRUCTURE - APPLICATIONS TO THE STUDY OF DROSOPHILA SALIVARY-GLAND NUCLEI .2. ALGORITHMS FOR MODEL ANALYSIS
LIGHT-MICROSCOPE BASED ANALYSIS OF 3-DIMENSIONAL STRUCTURE - APPLICATIONS TO THE STUDY OF DROSOPHILA SALIVARY-GLAND NUCLEI .2. ALGORITHMS FOR MODEL ANALYSIS
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DOI：
10.1111/j.1365-2818.1985.tb02583.x
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发表时间：
1985-01-01
影响因子：
2
通讯作者：
MATHOG, D
中科院分区：
文献类型：
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作者：
MATHOG, D
在黑腹果蝇中，来自同一个唾液腺的不同细胞核中多线染色体的排列方式存在显著差异。对这些细胞核模型进行目视检查不足以描绘出其结构中所有保守的特征。为了绕过这一限制，以一种与计算机操作兼容的格式构建了这些细胞核的模型。通过对这些模型应用一些简单的算法，进行了定量比较，从而揭示了许多细胞核共有的一些原本隐秘的特征。这里给出了几种用于描述和比较细胞核内染色体排列的算法的细节。
In Drosophila melanogaster there are significant differences in the way the polytene chromosomes are arranged in different nuclei from the same salivary gland. Visual inspection of the models of these nuclei was inadequate to delineate all of the features conserved in their structures. To bypass this limitation, models of these nuclei were constructed in a format compatible with computational manipulation. By applying some simple algorithms to these models, quantitative comparisons were made which revealed otherwise cryptic features common to many nuclei. Given here are the details of several algorithms for describing and comparing the arrangement of the chromosomes within the nuclei.