The rat endovascular perforation model of subarachnoid hemorrhage.

The rat endovascular perforation model of subarachnoid hemorrhage.
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DOI:
10.1007/978-3-319-04981-6_55
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发表时间:
2015-01-01
期刊:
Acta neurochirurgica. Supplement
影响因子:
--
通讯作者:
Sehba, Fatima A
Sehba, Fatima A
中科院分区:
其他
文献类型:
--
作者:
Sehba, Fatima A

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大鼠血管内穿孔模型被认为是最接近人类状况的复制品。自其发展以来,该模型已被广泛用于研究蛛网膜下腔出血(SAH)后的早期脑损伤。然而,像任何其他动物模型一样,它有优点和局限性。以下是对大鼠血管内穿孔SAH模型的简要回顾。其中一节专门讨论可用于克服模型局限性的技术考虑。
The rat endovascular perforation model is considered the closest replica of human condition. Since its development, this model has been extensively used to study early brain injury after subarachnoid hemorrhage (SAH). However, like any other animal model, it has advantages and limitations. The following is a brief review of the rat endovascular perforation SAH model. One section is dedicated to technical considerations that can be used to overcome the model limitations.