Surgical outcome in tuberous sclerosis complex: A Multicenter survey
Surgical outcome in tuberous sclerosis complex: A Multicenter survey
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DOI：
10.1111/j.1528-1167.2007.01112.x
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发表时间：
2007-08-01
期刊：
影响因子：
5.6
通讯作者：
Devinsky, Orrin
中科院分区：
文献类型：
--
作者：
Madhavan, Deepak;Schaffer, Sarah;Devinsky, Orrin
对70例癫痫缓解手术后的TSC患者进行了多中心的回顾性分析，发现癫痫起病年龄较小、婴儿痉挛病史、发作间期病灶(双侧与单侧)、术后无残留主要结节和较差的术后结果之间存在显著的相关性(p<；0.01)。胎儿多灶性、智力低下以及不一致的脑电和核磁共振数据显示出预后的负面趋势，但并不显著。
Multicenter, retrospective analysis of 70 subjects with TSC following surgery for relief of epilepsy revealed significant associations between younger age at seizure onset, present/prior history of infantile spasms, interictal focality (bilateral versus unilateral), and absence of residual postoperative predominant tuber, and poorer postoperative outcome (p < 0.01). fetal multifocality, mental retardation, and discordant EEG and MRI data showed a negative trend toward outcome, but were not significant.