Self-assembly of peptides into a β-barrel motif
Self-assembly of peptides into a β-barrel motif
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DOI：
10.1063/1.1649934
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发表时间：
2004-03-22
影响因子：
4.4
通讯作者：
Shea, JE
中科院分区：
文献类型：
--
作者：
Friedel, M;Shea, JE
我们报告的研究结果的自组装的四个最低限度的肽链与一个天然的β-桶结构。利用软势阱模拟细胞拥挤，在不同半径的封闭球体中进行分子动力学模拟。通过利用先前引入的用于非天然疏水相互作用的比例因子λ（0
We report the results of a study of the self-assembly of four minimalist peptide strands with a native beta-barrel structure. Using a soft-well potential to mimic cellular crowding, molecular dynamics simulations were performed in confining spheres of varying radii. By utilizing a previously introduced scaling factor lambda for the non-native hydrophobic interactions (0