HISTOLOGICAL STUDY OF BOVINE CORPORA LUTEA
HISTOLOGICAL STUDY OF BOVINE CORPORA LUTEA
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DOI：
10.3168/jds.s0022-0302(65)88360-6
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发表时间：
1965-01-01
影响因子：
3.5
通讯作者：
HANSEL, W
中科院分区：
文献类型：
--
作者：
DONALDSON, L;HANSEL, W
在发情周期的不同时间取出黄体，研究后，没有处理，处理催产素，催产素和HCG，催产素和牛LH，和HCG单独。这些研究支持了一个假说，即黄体细胞来源于卵泡的颗粒层和卵泡膜层。颗粒源性黄体细胞在发情周期的第4天左右发育成功能性黄体细胞，之后它们不再进行进一步的分裂。因此，粒层细胞来源的细胞具有有限的潜力。然而，来自内膜的较小的黄体细胞对血浆促黄体激素产生反应，繁殖并生长成大的黄体细胞。这些主要负责第4天后黄体的生长。在排卵前不久和无排卵（囊性）卵泡中，卵泡内膜和颗粒层出现黄体化。卵泡的崩溃和黄体的生长进行了描述，特别强调有丝分裂活动的模式前后的刺激与外源性促黄体激素和孕酮的浓度和内容。描述了黄体细胞的生长和退化。
Corpora lutea removed at various times during the estrous cycle were studied after no treatment, treatment with oxytocin, oxytocin and HCG, oxytocin and bovine LH, and with HCG alone. These studies supported a hypothesis that luteal cells are derived from both granulosa and theca layers of the follicle. The granulosa- derived luteal cells develop into functioning luteal cells by about Day 4 of the estrous cycle, after which they undergo no further divisions. Therefore, granulosa-derived cells have limited potential. However, the smaller luteal cells derived from the theca interna respond to plasma luteotropin, multiply and grow into large luteal cells. These are mainly responsible for growth of the corpus luteum following Day 4. There was luteinization of the theca interna and granulosa layers of the follicles shortly before ovulation and in anovulatory (cystic) follicles. The collapse of the follicle and growth of the corpus luteum were described, with special emphasis on the patterns of mitotic activity before and after stimulation with exogenous luteotropin and on progesterone concentrations and contents. Growth and degeneration of a luteal cell were described.