Impact of age, gender and cognitive functioning on pain perception
Impact of age, gender and cognitive functioning on pain perception
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DOI：
10.1159/000048937
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发表时间：
2002-03-01
期刊：
影响因子：
3.5
通讯作者：
Dubray, C
中科院分区：
文献类型：
--
作者：
Pickering, G;Jourdan, D;Dubray, C
背景。迄今为止，关于老年人伤害感受的实验数据是相互矛盾的，其中大多数是通过心理物理学方法获得的，很少同时关注受试者的认知状态和心理测量表现。目的：本研究的目的有两个：（1）评估年龄对实验性伤害感受阈值的影响，（2）研究年龄、性别、认知和心理测量表现与伤害感受阈值的相互作用。方法论。 (1) 将 42 名健康参与者（21 名男性和 21 名女性）分成两组，一组是年轻人，一组是老年人，比较热和机械刺激的伤害感受阈值（热和压力检测和耐受阈值）。 (2)老年组在听觉(感觉、耐受、辨别)和伤害性领域进行认知(简易测试)、心理测量(选择反应时间)和心理物理测试。结果：本研究表明（1）压力伤害感受随着年龄的增长而降低，尤其是男性，而热阈值没有改变；（2）认知功能、心理测量表现、对响亮声音的耐受性和对机械伤害性刺激的耐受性之间存在相关性。结论：我们的结果表明，在评估老年人的实验性伤害感受时，必须考虑认知和精神运动参数。需要进一步的研究来评估可能的报告偏差，并评估老年疼痛患者和轻度感觉、认知或运动受损的老年受试者中的这些相互作用。版权所有 (C) 2002 S. Karger AG，巴塞尔。
Background. Experimental data on nociception in the elderly have so far been contradictory and most of these have been obtained using psychophysical methods with little attention paid simultaneously to the state of cognition and the psychometric performance of the subjects. Objective: The aim of this study was twofold: (1) to evaluate the impact of age on experimental nociception thresholds, and (2) to investigate the interactions of age, sex, cognition and psychometric performance with nociception thresholds. Methodology. (1) Two groups, one young and one elderly, of 42 healthy participants each, 21 males and 21 females, were compared as regards nociception thresholds with thermal and mechanical stimuli (heat and pressure detection and tolerance thresholds). (2) The elderly group took cognitive (minimental test), psychometric (choice reaction time) and psychophysical tests in auditory (sensibility, tolerance, discrimination) and nociceptive fields. Results: This study shows that (1) pressure nociception decreases with age especially in males, while thermal thresholds are not modified, and (2) correlations exist between cognitive function, psychometric performance, tolerance to loud sounds and tolerance to mechanical noxious stimuli. Conclusion: Our results suggest that cognitive and psychomotor parameters have to be taken into account when assessing experimental nociception in the elderly. Further studies are needed to evaluate possible report biases and to assess these interactions in old patients with pain and in mildly sensory, cognitive or motor impaired elderly subjects. Copyright (C) 2002 S. Karger AG, Basel.