Rhodium-Catalyzed Selective Olefination of Arene Esters via C-H Bond Activation
Rhodium-Catalyzed Selective Olefination of Arene Esters via C-H Bond Activation
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DOI：
10.1021/ol200600p
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发表时间：
2011-05-06
期刊：
影响因子：
5.2
通讯作者：
Chang, Sukbok
中科院分区：
文献类型：
--
作者：
Park, Sae Hume;Kim, Ji Young;Chang, Sukbok
本文提出了一种新的苯甲酸酯和苯甲醛邻位烯烃化的催化方法。酯和甲醛单元被发现是有效的螯合基团，在集中活化的芳基C-H键邻位的Rh催化的氧化条件下的指导部分。该反应是高度区域选择性的，与一系列的苯甲酸酯和苯甲醛，使有效的烯化与丙烯酸酯，丙烯酸，和苯乙烯。
A new catalytic procedure of ortho-olefination of benzoates and benzaldehydes has been developed. Ester and carboxaldehyde units were revealed to be effective chelating groups in focusing the activation of aryl C-H bonds ortho to the directing moieties under the Rh-catalyzed oxidative conditions. The reaction is highly regioselective with a range of benzoates and benzaldehydes enabling the efficient olefination with acrylates, acrylic acid, and styrenes.