Clinical evaluation of a staphylococcal protein A immunoadsorption system in the treatment of myasthenia gravis patients
Clinical evaluation of a staphylococcal protein A immunoadsorption system in the treatment of myasthenia gravis patients
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葡萄球菌A蛋白免疫吸附系统治疗重症肌无力的临床评价
作者：
W. Benny;D. Sutton;J. Oger;V. Bril;M. McAteer;G. Rock
背景：血浆置换在重症肌无力治疗中的作用已得到证实，重症肌无力是一种自身免疫性疾病，以肌肉无力为特征，由循环中特异性抗乙酰胆碱受体的IgG抗体引起。然而，传统的血浆抗体去除方法是非选择性的，并且使用从人血浆中提取的替代液体（主要是白蛋白溶液）。
BACKGROUND: The role of plasma exchange is well established in the management of myasthenia gravis, an autoimmune disorder characterized by muscle weakness and caused by circulating IgG antibodies with specificity against the acetylcholine receptor. Plasma antibody removal by conventional means, however, is nonselective and uses replacement fluids (chiefly, albumin solution) derived from human plasma.