Copper inhibition of the thiobarbituric acid reaction in Bedlington terriers.
Copper inhibition of the thiobarbituric acid reaction in Bedlington terriers.
复制标题
铜抑制贝灵顿梗的硫代巴比妥酸反应。
DOI：
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发表时间：
1986
期刊：
影响因子：
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通讯作者：
Csallany As
中科院分区：
文献类型：
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作者：
Hultgren Bd;Menken Bz;Csallany As
The effect of copper on thiobarbituric acid (TBA) reaction values, an index of lipid peroxidation, was examined in Bedlington Terriers, healthy dogs, and rats. High hepatic concentrations of copper appeared to lower TBA values in the inherited, chronic, progressive hepatic degeneration of Bedlington Terriers, a disease associated with copper toxicosis. The suspected TBA inhibition was confirmed when Cu2+ was added to homogenates of healthy dog or rat liver or a malondialdehyde standard. The amount of copper added approximated that in diseased Bedlington Terriers. Because of the interference by copper, the TBA test was judged to be an inappropriate test for the evaluation of lipid peroxidation in samples containing high copper concentrations such as those in diseased Bedlington Terriers.
