Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration.
Gekko japonicus genome reveals evolution of adhesive toe pads and tail regeneration.
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日本壁虎基因组揭示了粘性趾垫和尾巴再生的进化。
DOI：
10.1038/ncomms10033
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发表时间：
2015-11-24
影响因子：
16.6
通讯作者：
Gu X
中科院分区：
文献类型：
--
作者：
Liu Y;Zhou Q;Wang Y;Luo L;Yang J;Yang L;Liu M;Li Y;Qian T;Zheng Y;Li M;Li J;Gu Y;Han Z;Xu M;Wang Y;Zhu C;Yu B;Yang Y;Ding F;Jiang J;Yang H;Gu X
爬行动物是形态和生理上最多样化的四足动物，经历了3亿年的适应性进化。在爬行类四足动物中，壁虎拥有几个有趣的特征，包括自动再生尾巴和在光滑表面上爬行的能力。本文对日本壁虎（Gekko japonicus, Schlegel’s Japanese Gecko）的基因组进行了测序，并研究了与其生理相关的遗传因子。我们得到了日本鳗鲡基因组序列的草图，全长2.55 Gb，注释了22,487个基因。比较基因组分析揭示了特定基因家族的扩展或减少与粘连刚毛的形成、夜间视觉和尾巴再生以及嗅觉的多样化有关。获得的基因组数据为爬行动物的适应性进化提供了强有力的遗传证据。
Reptiles are the most morphologically and physiologically diverse tetrapods, and have undergone 300 million years of adaptive evolution. Within the reptilian tetrapods, geckos possess several interesting features, including the ability to regenerate autotomized tails and to climb on smooth surfaces. Here we sequence the genome of Gekko japonicus (Schlegel’s Japanese Gecko) and investigate genetic elements related to its physiology. We obtain a draft G. japonicus genome sequence of 2.55 Gb and annotated 22,487 genes. Comparative genomic analysis reveals specific gene family expansions or reductions that are associated with the formation of adhesive setae, nocturnal vision and tail regeneration, as well as the diversification of olfactory sensation. The obtained genomic data provide robust genetic evidence of adaptive evolution in reptiles.