A single transcription factor promotes both yield and immunity in rice
A single transcription factor promotes both yield and immunity in rice
复制标题
单一转录因子可促进水稻的产量和免疫力。
DOI：
10.1126/science.aat7675
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发表时间：
2018-09-07
期刊：
影响因子：
56.9
通讯作者：
Chen, Xuewei
中科院分区：
文献类型：
--
作者：
Wang, Jing;Zhou, Lian;Chen, Xuewei
植物的免疫力往往不利于生长和产量。转录因子Ideal Plant Architecture 1（IPA1）可以减少无效分蘖并增加每穗粒数，从而提高水稻产量。在这里，我们报告说，较高的IPA1水平增强免疫力。从机制上讲，IPA1在其DNA结合结构域内的氨基酸Ser（163）处的磷酸化响应于真菌稻瘟病菌的感染而发生，并改变了IPA1的DNA结合特异性。磷酸化的IPA1与病原体防御基因WRKY45的启动子结合并激活其表达，从而增强抗病性。IPA1在感染后48小时内恢复到非磷酸化状态，重新支持高产所需的生长。因此，IPA1通过维持生长和免疫之间的平衡来促进产量和抗病性。
Plant immunity often penalizes growth and yield. The transcription factor Ideal Plant Architecture 1 (IPA1) reduces unproductive tillers and increases grains per panicle, which results in improved rice yield. Here we report that higher IPA1 levels enhance immunity. Mechanistically, phosphorylation of IPA1 at amino acid Ser(163) within its DNA binding domain occurs in response to infection by the fungus Magnaporthe oryzae and alters the DNA binding specificity of IPA1. Phosphorylated IPA1 binds to the promoter of the pathogen defense gene WRKY45 and activates its expression, leading to enhanced disease resistance. IPA1 returns to a nonphosphorylated state within 48 hours after infection, resuming support of the growth needed for high yield. Thus, IPA1 promotes both yield and disease resistance by sustaining a balance between growth and immunity.