Pausing for thought: engagement of left temporal cortex during pauses in speech
Pausing for thought: engagement of left temporal cortex during pauses in speech
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DOI：
10.1016/j.neuroimage.2003.09.041
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发表时间：
2004-01-01
期刊：
影响因子：
5.7
通讯作者：
McGuire, PK
中科院分区：
文献类型：
--
作者：
Kircher, TTJ;Brammer, MJ;McGuire, PK
连续言语中的停顿，特别是发生在从句中的停顿，被认为反映了即将到来的言语输出的计划。我们使用功能性磁共振成像（fMRI）来检查他们的神经相关性。六名志愿者在描述七个罗夏墨迹时被扫描，每个墨迹产生3分钟的讲话。在一个事件相关的设计，血氧水平依赖（BOLD）对比度的水平在短暂的言语停顿（平均持续时间1.3秒，SD 0.3秒）在公开的讲话进行了对比，在干预期间的清晰度。然后，我们研究了与发生在从句内的停顿和发生在语法连接处之间的停顿相关的活动。相对于说话时的清晰度，停顿与颞顶交界处左侧上级颞沟（BA 39/22）的激活相关。连续言语与双侧额下回（BA 44/45）、额中回（BA 8）和扣带回前回（BA 24）、颞中沟（BA 21/22）、枕叶皮质和小脑的更大激活相关。左颞激活是明显的停顿期间发生的条款，但不是在语法连接处的停顿。总之，在连续讲话的清晰度涉及额叶，颞叶和小脑区域，而暂停与左颞叶皮层的活动，特别是当这发生在一个子句。后者的发现是一致的证据表明，小句内停顿是一个相关的语音规划，特别是词汇检索。(C)2003年爱思唯尔公司All rights reserved.
Pauses during continuous speech, particularly those that occur within clauses, are thought to reflect the planning of forthcoming verbal output. We used functional Magnetic Resonance Imaging (fMRI) to examine their neural correlates. Six volunteers were scanned while describing seven Rorschach inkblots, producing 3 min of speech per inkblot. In an event-related design, the level of blood oxygenation level dependent (BOLD) contrast during brief speech pauses (mean duration 1.3 s, SD 0.3 s) during overt speech was contrasted with that during intervening periods of articulation. We then examined activity associated with pauses that occurred within clauses and pauses that occurred between grammatical junctions. Relative to articulation during speech, pauses were associated with activation in the banks of the left superior temporal sulcus (BA 39/22), at the temporoparietal junction. Continuous speech was associated with greater activation bilaterally in the inferior frontal (BA 44/45), middle frontal (BA 8) and anterior cingulate (BA 24) gyri, the middle temporal sulcus (BA 21/22), the occipital cortex and the cerebellum. Left temporal activation was evident during pauses that occurred within clauses but not during pauses at grammatical junctions. In summary, articulation during continuous speech involved frontal, temporal and cerebellar areas, while pausing was associated with activity in the left temporal cortex, especially when this occurred within a clause. The latter finding is consistent with evidence that within-clause pauses are a correlate of speech planning and in particular lexical retrieval. (C) 2003 Elsevier Inc. All rights reserved.