GTP-binding proteins in intracellular transport.
GTP-binding proteins in intracellular transport.
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DOI：
10.1016/0962-8924(92)90161-f
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发表时间：
1992-02-01
影响因子：
19
通讯作者：
Pfeffer, S R
中科院分区：
文献类型：
--
作者：
Pfeffer, S R
最近在细胞内蛋白质转运领域最令人兴奋的发现之一是发现参与胞吐和胞吞膜运输的许多细胞器在其细胞质表面上具有一个或多个Ras样GTP结合蛋白，这些蛋白对每个膜隔室具有特异性。这些蛋白质是有吸引力的候选人的运输囊泡的形成和运输囊泡的准确交付到其正确的目标的监管机构。
One of the most exciting recent discoveries in the area of intracellular protein transport is the finding that many organelles involved in exocytic and endocytic membrane traffic have one or more Ras-like GTP-binding proteins on their cytoplasmic face that are specific for each membranous compartment. These proteins are attractive candidates for regulators of transport vesicle formation and the accurate delivery of transport vesicles to their correct targets.