Beat-to-Beat, Reading-to-Reading, and Day-to-Day Blood Pressure Variability in Relation to Organ Damage in Untreated Chinese
Beat-to-Beat, Reading-to-Reading, and Day-to-Day Blood Pressure Variability in Relation to Organ Damage in Untreated Chinese
复制标题
未经治疗的中国人的逐搏、阅读和每日血压变异与器官损伤的关系。
DOI：
10.1161/hypertensionaha.113.02681
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发表时间：
2014-04-01
期刊：
影响因子：
8.3
通讯作者：
Staessen, Jan A.
中科院分区：
文献类型：
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作者：
Wei, Fang-Fei;Li, Yan;Staessen, Jan A.
靶器官损害是否与血压(BP)变异性独立于水平有关仍存在争议。我们通过对256名未接受高血压治疗的受试者进行10分钟逐跳、24小时动态血压记录和7天家庭血压记录来评估这些相关性。BP变异性指数是与平均值、最大-最小差值和平均实际变异性无关的变异性。使用多变量回归模型计算效应大小(标准化)。在每搏记录中，左心室重量指数(n=128)与收缩压无相关性(P>0.18)，但与3个收缩期变异性指数均呈正相关(+2.97~3.53g/m(2)；P
Whether target organ damage is associated with blood pressure (BP) variability independent of level remains debated. We assessed these associations from 10-minute beat-to-beat, 24-hour ambulatory, and 7-day home BP recordings in 256 untreated subjects referred to a hypertension clinic. BP variability indices were variability independent of the mean, maximum-minimum difference, and average real variability. Effect sizes (standardized ) were computed using multivariable regression models. In beat-to-beat recordings, left ventricular mass index (n=128) was not (P0.18) associated with systolic BP but increased with all 3 systolic variability indices (+2.97-3.53 g/m(2); P