CORNEAL ABLATION BY NANOSECOND, PICOSECOND, AND FEMTOSECOND LASERS AT 532 AND 625 NM
CORNEAL ABLATION BY NANOSECOND, PICOSECOND, AND FEMTOSECOND LASERS AT 532 AND 625 NM
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DOI：
10.1001/archopht.1989.01070010601038
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发表时间：
1989-04-01
影响因子：
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通讯作者：
FUJIMOTO, JG
中科院分区：
文献类型：
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作者：
STERN, D;SCHOENLEIN, RW;FUJIMOTO, JG
我们使用可见波长的纳秒 (ns)、皮秒和飞秒 (fs) 脉冲激光进行角膜切除。消融的阈值能量与脉冲持续时间的平方根成正比，范围从 100 fs 时的 2.5 微焦耳 (μJ) 到 8 ns 时的 500 μJ。使用皮秒和飞秒激光进行的切除在超微结构上优于使用纳秒激光进行的切除，并且在接近阈值的脉冲能量下，几乎与使用 193 nm 准分子激光进行的切除一样少的组织损伤。我们得出的结论是，可见光和近红外波长的超短脉冲激光可能是角膜手术中准分子激光的替代品，并且在某些眼内应用中可能比传统眼科钕-YAG激光具有优势。
We produced corneal excisions with nanosecond (ns)-, picosecond-, and femtosecond (fs)-pulsed lasers at visible wavelengths. The threshold energy for ablation was proportional to the square root of the pulse duration and varied from 2.5 microjoules (.mu.j) at 100 fs to 500 .mu.J at 8 ns. Excisions made with picosecond and femtosecond lasers were ultrastructurally superior to those made with nanosecond lasers and, at pulse energies near threshold, showed almost as little tissue damage as excisions made with excimer lasers at 193 nm. We conclude that ultra-short-pulsed lasers at visible and near-infrared wavelengths are a possible alternative to excimer lasers for corneal surgery and might have advantages over conventional ophthalmic neodymium-YAG lasers for some intraocular applications.