MORPHOLOGY OF GROUP-IB AFFERENT FIBER COLLATERALS IN THE SPINAL-CORD OF THE CAT
MORPHOLOGY OF GROUP-IB AFFERENT FIBER COLLATERALS IN THE SPINAL-CORD OF THE CAT
复制标题
DOI：
10.1113/jphysiol.1979.sp013001
复制
发表时间：
1979-01-01
影响因子：
5.5
通讯作者：
FYFFE, REW
中科院分区：
文献类型：
--
作者：
BROWN, AG;FYFFE, REW
将辣根过氧化物酶（HRP）注入麻醉猫的单Ib肌传入纤维。随后，组织化学可以确定腰骶脊髓轴突及其侧支的形态。对11个轴突进行染色，其中7个来自腓肠肌外侧-比目鱼肌，1个来自腓肠肌内侧，3个来自胫后神经支配的肌肉。其中10个轴突被追踪到背根，除了1个轴突（来自胫骨后神经）外，其余轴突都在进入脊髓时分叉。每个轴突的5.1 - 9.9 mm被染色，纤维以100-2300 μ的间隔发出84条侧枝。M，平均间距约为900 μ M。下行轴突分支（细）侧枝间距一般小于上行分支侧枝间距。所有Ib侧枝均具有特征形态。侧支在分叉前沿背角至IV或V椎板的直接路径向颅骨行进。它们广泛分布在中间区域，主要分布在第四层和第七层的背侧。偶尔，在IV层和v层中可以看到更背侧的不太广泛的分枝。单个侧枝分枝的上-尾侧范围限制在200-400 .mu。M，相邻抵押品之间没有重叠。每个终端树形产生56-384个钮扣，主要为过境型。结果讨论与先前的解剖和电生理研究。
Horseradish peroxidase (HRP) was injected into single Ib muscle afferent fibers in anesthetized cats. Subsequently, histochemistry allowed the morphology of the axons and their collaterals in the lumbosacral spinal cord to be determined. Ib axons (11) were stained, 7 from lateral gastrocnemius-soleus, 1 from medial gastrocnemius and 3 from muscles innervated by the posterior tibial nerve. Of the axons 10 were traced into the dorsal roots and all but 1 (from the posterior tibial nerve) bifurcated upon entering the cord. Between 5.1 and 9.9 mm of each axon was stained and the fibers gave off 84 collaterals at intervals of 100-2300 .mu.m, at an average spacing of about 900 .mu.m. The spacing between collaterals on the (finer) descending axon branches was generally less than the intervals between collaterals on ascending branches. All Ib collaterals had a characteristic morphology. The collaterals coursed cranially on a direct path through the dorsal horn to lamina IV or V before branching. They arborized widely in the intermediate region, mainly in lamina IV and in the dorsal part of lamina VII. Occasionally, less extensive arborizations were seen more dorsally in lamina IV and V. The rostro-caudal extent of individual collateral arborizations was limited to 200-400 .mu.m and there was no overlap between adjacent collaterals. Each terminal arborization gave rise to 56-384 boutons, mainly of the en passant type. The results are discussed in relation to previous anatomical and electrophysiological studies.