Viral vaccines for farmed finfish
Viral vaccines for farmed finfish
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DOI：
10.1007/s13337-013-0186-4
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发表时间：
2014-01-01
期刊：
影响因子：
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通讯作者：
Allnutt, F. C. Thomas
中科院分区：
文献类型：
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作者：
Dhar, Arun K.;Manna, Sanjib K.;Allnutt, F. C. Thomas
在过去十年中，尽管面临许多挑战，但全球水产养殖的年平均增长率约为6%。病毒性疾病是威胁全球鱼类养殖可持续发展的主要挑战之一。在商业养鱼中，为养鱼接种疫苗对减轻病毒性疾病起着重要作用。本文综述了造成严重经济损失的主要病毒性疾病和对水产养殖业构成潜在威胁的新发疾病。讨论了养殖鱼类中病毒疫苗的现状，特别是近年来获得许可并现已商业化的不同类型疫苗，以及这些疫苗的输送途径，包括每种输送方法的优缺点。此外，本文概述了近年来文献中报道的不同实验性疫苗，并强调未来需要开发成本效益高、易于在农场层面应用的口服疫苗。
Over the past decade, aquaculture has grown at an average annual growth rate of approximately 6 % worldwide despite many challenges. Viral diseases are one of the major challenges that are threatening a sustainable growth of finfish farming globally. Vaccination of farmed fish plays an important role in commercial fish farming to mitigate viral diseases. In this review, we summarized the major viral diseases that have caused serious economic losses, and emerging diseases that pose a potential threat to aquaculture. The current status of viral vaccines in farmed fish are discussed, particularly the different types of vaccines that were licensed in recent years and are now commercially available, and the routes of delivery of those vaccines including the merits and demerits of each of these delivery method. Furthermore, the article provides an overview of different experimental vaccines that have been reported in the literatures in recent years besides highlighting the future need for developing cost-effective, oral vaccines that can be easily applicable at farm level.