Three-dimensional electroanatomical voltage mapping and histologic evaluation of myocardial substrate in right ventricular outflow tract tachycardia
Three-dimensional electroanatomical voltage mapping and histologic evaluation of myocardial substrate in right ventricular outflow tract tachycardia
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DOI：
10.1016/j.jacc.2007.11.027
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发表时间：
2008-02-19
影响因子：
24
通讯作者：
Thiene, Gaetano
中科院分区：
文献类型：
--
作者：
Corrado, Domenico;Basso, Cristina;Thiene, Gaetano
目的探讨三维电解剖电压标测(EVM)对特发性右室流出道心动过速(RVOT)和致心律失常性右室心肌病/发育不良(ARVC/D)的鉴别诊断价值。背景右室EVM已被证明能可靠地识别ARVC/D患者的低电压区域(“电解剖疤痕”)，在ARVC/D患者中对应于纤维脂肪心肌替代区域。方法研究对象为27例RVOT心动过速患者(男15例，女12例，年龄33.9±1.8岁)，无右室扩张/功能障碍的超声/血管造影证据结果27例患者中有20例(74%，A组)电解剖电压标测正常，心电图电压和GT正常；1.5 mV贯穿整个房车。另7例(26%，13组)显示-gt；=1(1.4+/-07)RV电肛门瘢痕面积(S)(双极电压
Objectives We tested whether 3-dimensional electroanatomical voltage mapping (EVM) may help in the differential diagnosis between idiopathic right ventricular outflow tract (RVOT) tachycardia and arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D).Background Right ventricular EVM has been demonstrated to reliably identify low-voltage regions ("electroanatomical scar"), which in patients with ARVC/D correspond to areas of fibrofatty myocardial replacement.Methods The study population comprised 27 patients (15 men and 12 women, age 33.9 +/- 1 8 years) with RVOT tachycardia and no echocardlographic/angiographic evidence of right ventricular (RV) dilation/dysfunction, who underwent EVM and endomyocardial biopsy (EMB) for characterization of ventricular tachycardia (VT) substrate before catheter ablation.Results Electroanatomical voltage mapping was normal in 20 of 27 patients (74%, group A), with electrogram voltage >1.5 mV throughout the RV. The other 7 patients (26%, group 13) showed >= 1 (1.4 +/- 07) RV electroanatornical scar area(s) (bipolar voltage