Penetration of propylene glycol into dentine
Penetration of propylene glycol into dentine
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DOI：
10.1046/j.1365-2591.2002.00482.x
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发表时间：
2002-04-01
影响因子：
5
通讯作者：
Hoshino, E
中科院分区：
文献类型：
--
作者：
Cruz, EV;Kota, K;Hoshino, E
目的研究丙二醇对牙根本质的渗透作用。方法将丙二醇中的红花素O和蒸馏水中的红花素O分别引入根管中，有人工涂抹层和无人工涂抹层。用分光光度法测定染料在牙本质小管中的扩散。用丙二醇和蒸馏水作为载体，测定了染料通过根尖孔排出所需的时间。使用Adobe Photoshop和NIH Image Software评估染料在根裂面渗透的程度和面积。结果丙二醇可使染料更快地通过根尖孔排出。丙二醇对染料的渗透面积和深度显著大于蒸馏水（P < 0.0001）。涂抹层明显延缓了染料的渗透。结论丙二醇通过根管系统快速、有效地递送染料，提示丙二醇在管内药物递送中具有潜在的应用前景。
Aim This study aimed to evaluate penetration of propylene glycol into root dentine.Methodology Safranin O in propylene glycol and in distilled water were introduced into root canals with and without artificial smear layer. Dye diffusion through dentinal tubules was determined spectrophotometrically. The time required for dye to exit through the apical foramen using propylene glycol and distilled water as vehicles was also determined. The extent and areas of dye penetration on the split surfaces of roots were assessed using Adobe Photoshop and NIH Image Software.Results Propylene glycol allowed dye to exit faster through the apical foramen. The area and depth of dye penetration with propylene glycol was significantly greater than with distilled water (P < 0.0001). Smear layer significantly delayed the penetration of dye.Conclusion Propylene glycol delivered dye through the root canal system rapidly and more effectively indicating its potential use in delivering intracanal medicaments.