Development of a compact DOI-TOF detector module for high-performance PET systems
Development of a compact DOI-TOF detector module for high-performance PET systems
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开发用于高性能 PET 系统的紧凑型 DOI-TOF 探测器模块
DOI：
10.1007/s41365-017-0202-2
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发表时间：
2017
影响因子：
2.8
通讯作者：
Ma Tian-Yu
中科院分区：
文献类型：
--
作者：
Wei Qing-Yang;Xu Tian-Peng;Dai Tian-Tian;Wang Shi;Liu Ya-Qiang;Gu Yu;Ma Tian-Yu
为了提高PET成像的空间分辨率和信噪比，本文提出了结合交互深度（DOI）和飞行时间（TOF）能力的PET检测器模块的设计和性能评估。探测器模块由交错双层LYSO块组成，晶体为2mm × 2mm × 7mm。mr兼容SiPM传感器（MicroFJ-30035-TSV, SensL）组装成8 × 8阵列。快速和慢速输出的SiPM信号由128通道ASIC芯片读出。为了测试其性能，在检测器顶部放置22na点源，获得了一个洪水直方图，并测量了每个晶体的能量分辨率和符合分辨时间（CRT）值。泛流直方图显示两层中晶体分离良好。511 keV时，底层和顶层的平均能量分辨率分别为14.0%和12.7%。单晶的平均阴极射线管在底层和顶层分别为635和565 ps。综上所述，紧凑的DOI-TOF PET检测器模块具有优异的晶体识别能力、良好的能量分辨率和合理的时间分辨率，在临床TOF PET、PET/MRI和脑PET系统中具有良好的应用前景。
To increase spatial resolution and signal-to-noise ratio in PET imaging, we present in this paper the design and performance evaluation of a PET detector module combining both depth-of-interaction (DOI) and time-of-flight (TOF) capabilities. The detector module consists of a staggered dual-layer LYSO block with 2 mm × 2 mm × 7 mm crystals. MR-compatible SiPM sensors (MicroFJ-30035-TSV, SensL) are assembled into an 8 × 8 array. SiPM signals from both fast and slow outputs are read out by a 128-channel ASIC chip. To test its performance, a flood histogram is acquired with a22Na point source on top of the detector, and the energy resolution and the coincidence resolving time (CRT) value for each individual crystal are measured. The flood histogram shows excellent crystal separation in both layers. The average energy resolution at 511 keV is 14.0 and 12.7% at the bottom and top layers, respectively. The average CRT of a single crystal is 635 and 565 ps at the bottom and top layers, respectively. In conclusion, the compact DOI–TOF PET detector module is of excellent crystal identification capability, good energy resolution and reasonable time resolution and has promising application prospective in clinical TOF PET, PET/MRI, and brain PET systems.