Biology and genome of a newly discovered sibling species of Caenorhabditis elegans.
Biology and genome of a newly discovered sibling species of Caenorhabditis elegans.
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DOI：
10.1038/s41467-018-05712-5
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发表时间：
2018-08-10
影响因子：
16.6
通讯作者：
Kikuchi T
中科院分区：
文献类型：
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作者：
Kanzaki N;Tsai IJ;Tanaka R;Hunt VL;Liu D;Tsuyama K;Maeda Y;Namai S;Kumagai R;Tracey A;Holroyd N;Doyle SR;Woodruff GC;Murase K;Kitazume H;Chai C;Akagi A;Panda O;Ke HM;Schroeder FC;Wang J;Berriman M;Sternberg PW;Sugimoto A;Kikuchi T
模式生物秀丽隐杆线虫的“兄弟”物种长期以来一直被用于比较分析，这将使生物现象的深层进化解释成为可能。在这里，我们描述了C的第一个兄弟物种。elegans、秀丽隐杆线虫C.异翅亚目;例如，分离自日本冲绳的无花果树。研究了该虫的形态、发育过程和行为。inopinata与C.优美的123 Mb C.通过对C. inopinata的基因组进行测序，将其组装成6条核染色体，从而描绘了小杆线虫的基因组进化，并揭示了其独特的特征，例如高度扩展的转座因子，这些转座因子可能有助于小杆线虫的基因组进化。inopinata。此外，C. inopinata在化学感受器基因家族中表现出大量的基因丢失，这可能与其有限的栖息地面积有关。我们已经开发了C的遗传和分子技术。inopinata;因此C. inopinata为比较进化研究提供了一个令人兴奋的新平台。小杆线虫是重要的模式生物。在这里，作者报告了C. habditis inopinata的生物学和基因组，C. habditis inopinata是C. elegans，并开发C. inopinata。
A ‘sibling’ species of the model organism Caenorhabditis elegans has long been sought for use in comparative analyses that would enable deep evolutionary interpretations of biological phenomena. Here, we describe the first sibling species of C. elegans, C. inopinata n. sp., isolated from fig syconia in Okinawa, Japan. We investigate the morphology, developmental processes and behaviour of C. inopinata, which differ significantly from those of C. elegans. The 123-Mb C. inopinata genome was sequenced and assembled into six nuclear chromosomes, allowing delineation of Caenorhabditis genome evolution and revealing unique characteristics, such as highly expanded transposable elements that might have contributed to the genome evolution of C. inopinata. In addition, C. inopinata exhibits massive gene losses in chemoreceptor gene families, which could be correlated with its limited habitat area. We have developed genetic and molecular techniques for C. inopinata; thus C. inopinata provides an exciting new platform for comparative evolutionary studies. Caenorhabditis nematodes are important model organisms. Here, the authors report the biology and genome of Caenorhabditis inopinata, a first sibling species of C. elegans, and develop genetic and molecular techniques for C. inopinata.