Can the blood alcohol concentration be a predictor for increased hospital complications in trauma patients involved in motor vehicle crashes?
Can the blood alcohol concentration be a predictor for increased hospital complications in trauma patients involved in motor vehicle crashes?
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DOI：
10.3390/ijerph7031174
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发表时间：
2010-03
影响因子：
--
通讯作者：
Fleming MF
中科院分区：
文献类型：
--
作者：
Kapur JH;Rajamanickam V;Fleming MF
本报告的目的是评估机动车事故后入院患者的不同血液酒精浓度 (BAC) 水平与医院并发症之间的关系。该研究的数据是通过美国外科医生学会国家创伤登记处 (NTRACS) 对威斯康星大学医院创伤登记处 1999 年至 2007 年间的创伤登记处进行回顾性审查收集的。在 3729 名患者中，2210 名患者 (59%) BAC 呈阴性，338 名患者 (9%) <100 mg/dL，538 名患者 (14%) 100–199 mg/dL，643 名患者 (17%) >200 mg/dL。百分之四十六的患者患有一种或多种医院相关并发症。与不饮酒组相比，三个饮酒组发生酒精戒断的优势比 (OR) 分别为 12.02 (CI 7.0–20.7)、16.81 (CI 10.4–27.2) 和 30.96 (CI 19.5–49.2)，因为 BAC 增加并具有明显的剂量反应效应。虽然四组中创伤后住院总事件的发生频率没有显着差异，但高 BAC 组的感染、凝血功能障碍、中枢神经系统事件和肾脏并发症发生率较低。需要进行前瞻性研究，以更准确地估计酒精使用障碍患者和机动车事故发生时醉酒者发生医院并发症的频率。该研究支持使用常规 BAC 来预测酒精戒断高风险患者并尽早开始酒精戒毒。
The goal of this report is to assess the relationship of varying levels of blood alcohol concentration (BAC) and hospital complications in patients admitted after motor vehicle crashes. Data for the study was collected by a retrospective review of the University of Wisconsin Hospital trauma registry between 1999 and 2007 using the National Trauma Registry of the American College of Surgeons (NTRACS). Of 3729 patients, 2210 (59%) had a negative BAC, 338 (9%) <100 mg/dL, 538 (14%) 100–199 mg/dL, and 643 (17%) >200 mg/dL. Forty-six percent of patients had one or more hospital related complications. The odds ratio (OR) for the occurrence of alcohol withdrawal in the three alcohol groups compared to the no alcohol group was 12.02 (CI 7.0–20.7), 16.81 (CI 10.4–27.2), and 30.96 (CI 19.5–49.2) as BAC increased with a clear dose response effect. While there were no significant differences in the frequency of the total hospital events following trauma across the four groups, rates of infections, coagulopathies, central nervous system events and renal complications were lower in the high BAC group. Prospective studies are needed to more precisely estimate the frequency of hospital complications in patients with alcohol use disorders and in persons intoxicated at the time of the motor vehicle accident. The study supports the use of routine BAC to predict patients at high risk for alcohol withdrawal and the early initiation of alcohol detoxification.
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影响因子：
3
作者：
Angles, Erik M.;Robinson, Thomas N.;Moore, Ernest E.
通讯作者：
Moore, Ernest E.
DOI：
10.1097/00005373-198408000-00001
发表时间：
1984-01-01
影响因子：
--
作者：
LUNA, GK;MAIER, RV;ORESKOVICH, MR
通讯作者：
ORESKOVICH, MR
DOI：
10.1097/ta.0b013e318031aa7f
发表时间：
2007-03-01
影响因子：
--
作者：
Rootman, Daniel B.;Mustard, Robert;Ahmed, Najma
通讯作者：
Ahmed, Najma
影响因子：
2.3
作者：
Bird, Melanie D.;Choudhry, Mashkoor A.;Kovacsa, Elizabeth J.
通讯作者：
Kovacsa, Elizabeth J.
DOI：
10.1097/ta.0b013e31814b2c4d
发表时间：
2008-07
期刊：
The Journal of trauma
影响因子：
--
作者：
Pandharipande P;Cotton BA;Shintani A;Thompson J;Pun BT;Morris JA Jr;Dittus R;Ely EW
通讯作者：
Ely EW