Acceptability of HIV Pre-exposure Prophylaxis (PrEP) Among People Who Inject Drugs (PWID) in a Canadian Setting

Acceptability of HIV Pre-exposure Prophylaxis (PrEP) Among People Who Inject Drugs (PWID) in a Canadian Setting
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DOI:
10.1007/s10461-014-0867-z
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发表时间:
2015-05-01
期刊:
影响因子:
4.4
通讯作者:
Marshall, Brandon D. L.
Marshall, Brandon D. L.
中科院分区:
医学2区
文献类型:
--
作者:
Escudero, Daniel J.;Kerr, Thomas;Marshall, Brandon D. L.

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最近的一项临床试验提供的证据表明,暴露前预防(PrEP)有可能预防注射吸毒者(PWID)感染艾滋病毒。我们研究了加拿大温哥华(n = 543)HIV阴性PWID使用PrEP的意愿,以告知PrEP实施工作。三分之一(35.4%)表示愿意使用PrEP,调整后的模型表明,年龄较小,没有固定的工作,需要帮助注射,从事性工作,并报告多个最近的性伴侣与愿意使用PrEP。虽然使用PrEP的意愿很低,PrEP是可以接受的一些PWID在艾滋病毒感染的高风险。
A recent clinical trial provided evidence that pre-exposure prophylaxis (PrEP) has the potential to prevent HIV infection among people who inject drugs (PWID). We examined willingness to use PrEP among HIV-negative PWID in Vancouver, Canada (n = 543) to inform PrEP implementation efforts. One third (35.4 %) expressed willingness to use PrEP, with adjusted models indicating that younger age, no regular employment, requiring help injecting, engaging in sex work, and reporting multiple recent sexual partners were positively associated with willingness to use PrEP. Although willingness to use PrEP was low, PrEP was acceptable to some PWID at heightened risk for HIV infection.