Identification of clinically important ascomycetous yeasts based on nucleotide divergence in the 5' end of the large-subunit (26S) ribosomal DNA gene

Identification of clinically important ascomycetous yeasts based on nucleotide divergence in the 5' end of the large-subunit (26S) ribosomal DNA gene
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DOI:
10.1128/jcm.35.5.1216-1223.1997
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发表时间:
1997-05-01
影响因子:
9.4
通讯作者:
Robnett, CJ
Robnett, CJ
中科院分区:
医学2区
文献类型:
--
作者:
Kurtzman, CP;Robnett, CJ

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比较了临床上重要的念珠菌和相关生物在大亚基(26S)核糖体DNA(RDNA)基因5‘端的核苷酸差异程度;该rDNA区域具有足够的可变性,可以可靠地分离所有已知的临床重要酵母物种,在所描述的204个物种中,有21个似乎是先前描述的生物的同义词,提出了物种之间的系统发育关系。
Clinically important species of Candida and related organisms were compared for extent of nucleotide divergence in the 5' end of the large-subunit (26S) ribosomal DNA (rDNA) gene;This rDNA region is sufficiently variable to allow reliable separation of all known clinically significant yeast species, Of the 204 described species examined, 21 appeared to be synonyms of previously described organisms, Phylogenetic relationships among the species are presented.