Impact of a pharmaceutical care program in a community pharmacy on patients with dyslipidemia
Impact of a pharmaceutical care program in a community pharmacy on patients with dyslipidemia
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DOI：
10.1345/aph.1e347
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发表时间：
2005-05-01
影响因子：
2.9
通讯作者：
Cárcamo, CA
中科院分区：
文献类型：
--
作者：
Paulós, CP;Nygren, CEA;Cárcamo, CA
背景：药物使用不当是当今卫生保健中的一个重大问题。通过更好地控制患者的药物治疗，可以解决这一问题。目的：在社区药房环境中为血脂异常患者设计一个药学服务方案，提供药物依从性和生活方式改变方面的教育，同时强调实现胆固醇目标以确保改善生活质量的重要性。方法：门诊药房的患者自愿接受为期16周的调查。虽然干预组和对照组都进行了调查，但随机选择的干预组的访谈更频繁、更全面。胆固醇、甘油三酯、葡萄糖、体重、危险因素、药物相关问题（DRPs）和生活质量在研究开始时通过一项调查进行测量，并在研究结论中不断测量。结果：干预组共检出drp 26例，其中解决24例；对照组共检出DRPs 26个，其中溶解5个。当比较干预组的初始和最终血胆固醇水平时，平均降低27.0 +/- 41.1 mg/dL (p = 0.0266)；在对照组中，平均血液胆固醇水平平均下降1.4 +/- 37.2 mg/dL （p = 0.6624）。干预组甘油三酯水平平均下降50.5 +/- 80.3 mg/dL (p = 0.0169)，对照组甘油三酯水平平均上升29.6 +/- 118.5 mg/dL （p = 0.1435）。干预后，干预组的生活质量得到改善。结论：零售药店在适当的环境下制定的短期药学服务计划可能有助于改善血脂值、心血管疾病危险因素和患者的生活质量。
BACKGROUND: Inappropriate use of medications is a significant problem in health care today. A possible solution to this problem may be achieved through better control of patients' drug therapy.OBJECTIVE: To design a pharmaceutical care program for dyslipidemic patients within a community pharmacy setting that provides education in the areas of medication compliance and lifestyle modifications, while emphasizing the importance of achieving cholesterol goals to ensure improvement in quality of life.METHODS: Patients at an outpatient pharmacy volunteered to be surveyed for 16 weeks. Although both the intervention and control groups were surveyed, the randomly selected intervention group was interviewed more frequently and more comprehensively. Cholesterol, triglycerides, glucose, weight, risk factors, drug-related problems (DRPs), and quality of life were measured via a survey at the onset of the study and continually measured unfit the study's conclusion.RESULTS: In the intervention group, 26 DRPs were detected, of which 24 were resolved; in the control group, 26 DRPs were detected, of which 5 were resolved. When comparing initial and final blood cholesterol levels in the intervention group, the mean decrease was 27.0 +/- 41.1 mg/dL (p = 0.0266); in the control group, the average blood cholesterol level decreased by a mean of 1.4 +/- 37.2 mg/dL (p = 0.6624). In the intervention group, the triglyceride level decreased an average of 50.5 +/- 80.3 mg/dL (p = 0.0169), while the control group experienced a mean triglyceride level increase of 29.6 +/- 118.5 mg/dL (p = 0.1435). As a result of the intervention, the quality of life in the intervention group was improved.CONCLUSIONS: Short-term pharmaceutical care plans developed in a retail pharmacy within the proper setting may contribute to improved blood lipid values, cardiovascular disease risk factors, and patients' quality of life.