Forcespun polyvinylpyrrolidone/copper and polyethylene oxide/copper composite fibers and their use as antibacterial agents
Forcespun polyvinylpyrrolidone/copper and polyethylene oxide/copper composite fibers and their use as antibacterial agents
复制标题
DOI：
10.1002/app.51773
复制
发表时间：
2021-10
影响因子：
3
通讯作者：
Md Toukir Hasan;Ramiro Gonzalez;A. Munoz;L. Materon;J. Parsons;M. Alcoutlabi
中科院分区：
文献类型：
--
作者：
Md Toukir Hasan;Ramiro Gonzalez;A. Munoz;L. Materon;J. Parsons;M. Alcoutlabi
采用PVP/乙醇和PEO/水溶液离心纺丝的方法，分别在聚乙烯吡咯烷酮（PVP）和聚氧聚乙烯（PEO）纤维基质中制备了铜纳米颗粒（CuNPs）。本研究的主要重点是研究复合纤维对大肠杆菌的抗菌活性。大肠杆菌)和蜡样芽孢杆菌(B。仙人掌)细菌。在成纤维过程中，仔细选择喷丝器转速、喷丝器与收集器的距离、相对湿度等离心纺丝参数，以获得长而连续的纤维。利用扫描电子显微镜、X射线衍射、能量色散X射线能谱和热重分析对两种复合纤维进行了结构和形态分析。在抗菌试验中，PVP/Cu和PEO/Cu复合纤维膜对ste的抑制率分别为99.98%和99.99%。coliandB。分别cereusbacteria。基本上，CuNPs在纳米水平上很好地嵌入纤维膜，这有助于通过使细胞的化学结构失活来抑制细菌的功能。这种从强压复合纤维中获得的有效抗菌剂可能是生物医学应用的有希望的候选者。
Copper nanoparticles (CuNPs) embedded in polyvinylpyrrolidone (PVP) and polyethylene oxide (PEO) fiber‐matrices were prepared through centrifugal spinning of PVP/ethanol and PEO/aqueous solutions, respectively. The prime focus of the current study is to investigate the antibacterial activity of composite fibers againstEscherichia coli(E. coli) andBacillus cereus(B. cereus) bacteria. During the fiber formation, the centrifugal spinning parameters such as spinneret rotational speed, spinneret to collector distance, and relative humidity were carefully chosen to obtain long and continuous fibers. The structural and morphological analyses of both composite fibers were investigated using scanning electron microscopy, X‐ray diffraction, energy‐dispersive X‐ray spectroscopy, and thermogravimetric analysis. In the antibacterial test, PVP/Cu and PEO/Cu composite fibrous membranes exhibited inhibition efficiency of 99.98% and 99.99% againstE. coliandB. cereusbacteria, respectively. Basically, CuNPs were well embedded in the fibrous membrane at the nanoscale level, which facilitated the inhibition of bacterial functions through the inactivation of the chemical structure of the cells. Such an effective antibacterial agent obtained from forcespun composite fibers could be promising candidates for biomedical applications.