Dose and time dependencies of 5‐fluorouracil pharmacokinetics
Dose and time dependencies of 5‐fluorouracil pharmacokinetics
复制标题
5-氟尿嘧啶药代动力学的剂量和时间依赖性
DOI:
--
复制
发表时间:
2000
期刊:
影响因子:
--
通讯作者:
E. Chatelut
中科院分区:
文献类型:
--
作者:
C. Terret;Eric Erdociain;R. Guimbaud;M. Boisdron;H. McLeod;Régine Féty‐Deporte;T. Lafont;E. Gamelin;R. Bugat;P. Canal;E. Chatelut
The purpose of this study was to examine the interpatient and intrapatient variability of the Michaelis‐Menten plasma parameters of 5‐fluorouracil administered according to a schedule combining a bolus of 400 mg/m2 followed by 22‐hour infusion of 600 mg/m2 for 2 consecutive days. Patients: A pharmacokinetic population approach was used to analyze the data from 21 patients with colorectal cancer.
影响因子:
2.9
作者:
Krzyzanski, Wojciech;Wiczling, Pawel;Balser, Sigrid
通讯作者:
Balser, Sigrid