EFFECT OF STIMULATION OF CERVICAL SYMPATHETIC CHAIN ON RETINAL OXYGEN-TENSION AND ON UVEAL, RETINAL AND CEREBRAL BLOOD-FLOW IN CATS
EFFECT OF STIMULATION OF CERVICAL SYMPATHETIC CHAIN ON RETINAL OXYGEN-TENSION AND ON UVEAL, RETINAL AND CEREBRAL BLOOD-FLOW IN CATS
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DOI：
10.1111/j.1748-1716.1973.tb05436.x
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发表时间：
1973-01-01
期刊：
影响因子：
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通讯作者：
BILL, A
中科院分区：
文献类型：
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作者：
ALM, A;BILL, A
在猫身上研究了刺激颈交感神经链对视网膜、葡萄膜不同部位、脑不同部位和其他组织血流量的影响。5 Hz在5个实验中降低了靠近视网膜的玻璃体中的氧分压。为6. 15 μm标记微球用于定量测定血流量。在9只正常碳酸血症猫和4只高碳酸血症猫中进行10 Hz单侧刺激1 min，在5只正常碳酸血症猫中进行15-30 min。结果表明，通过视网膜最内层的血流受到交感神经刺激的影响。葡萄膜内的血管阻力在所有三个组中都大大增加，没有“自动调节逃逸”的迹象。这种作用在睫状突中最明显，在睫状肌中最小。在腮腺、舌头和咬肌中观察到“自动调节逃逸”，其中1分钟刺激导致血流量平均减少82-99%，而15-30分钟刺激后减少6-56%。两组中的脑血流量均未显示统计学显著性降低，表明交感神经在猫的总脑血流量调节中的定量作用较小。
The effects of stimulation of the cervical sympathetic chain on blood flow through the retina, the different parts of the uvea, different parts of the brain and some other tissues were studied in cats. 5 Hz reduced the oxygen tension in the vitreous body close to the retina in 5 expts. of 6. 15 μm labelled microspheres were used for quantitative determinations of blood flow. Unilateral stimulation at 10 Hz was performed for 1 min in 9 normocapnic and in 4 hypercapnic cats and for 15–30 min in 5 normocapnic cats. The results suggest that blood ffow through the innermost layers of the retina is influenced by sympathetic stimulation. The vascular resistance within the uvea was much increased in all three groups with no indications for “autoregulatory escape”. The effect was most pronounced in the ciliary processes and least in the ciliary muscle. “Autoregulatory escape” was seen in the parotid gland, the tongue and the masseter muscle, where 1 min stimulation caused mean reductions in blood flow by 82–99% compared to 6–56% after 15–30 min stimulation. Cerebral blood flow showed no statistically significant reductions in either group indicating a quantitatively minor role for the sympathetics in regulation of total cerebral blood flow in cats.