Clinical and Prognostic Factors for Melanoma of the Skin Using SEER Registries: Collaborative Stage Data Collection System, Version 1 and Version 2
Clinical and Prognostic Factors for Melanoma of the Skin Using SEER Registries: Collaborative Stage Data Collection System, Version 1 and Version 2
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DOI：
10.1002/cncr.29050
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发表时间：
2014-12-01
期刊：
影响因子：
6.2
通讯作者：
Dickie, Lois
中科院分区：
文献类型：
--
作者：
Kosary, Carol L.;Altekruse, Sean F.;Dickie, Lois
本文的目的是评估作为协作阶段（CS）第2版的一部分，收集的关于部位特异性因素（SSF）的数据的完整性，以及从美国癌症联合委员会（AJCC）第6版到第7版指南对阶段分布的过渡的影响。和最终结果（SEER）登记研究（SEER-18）进行了分析。对7个SSF的未知病例的分类进行了检查，沿着与2004年至2010年的分期趋势以及2010例AJCC第6版和第7版分期分布的差异进行了研究。对于其余SSF，36-81%的病例编码为未知。除IA期和INOS期外，AJCC第6版和第7版之间的分期分布在不同时间相对一致（未另行说明），AJCC第6版和第7版指南2010年的病例数发生了变化。结论AJCC第6版和第7版指南2010年的病例数发生了IA期和INOS期的变化例这归因于SSF 7（原发性肿瘤有丝分裂计数/率）编码为未知的病例数量较多。编码为未知的病例百分比因SSF而异。数据完整性是CS版本2中引入的SSF的一个问题。Cancer 2014;120（23 suppl）：3807-14. (c)2014年美国癌症协会。这份报告强调了随着TNM从AJCC第6版移至第7版，皮肤黑色素瘤的协作阶段的变化。不同时间段以及AJCC第6版和第7版之间的分期分布相对一致，但IA期除外，由于第7版IA期分配中增加了有丝分裂率，并且大量病例缺失了该信息，因此观察到了向INOS期的转变。
BACKGROUNDThe objectives of this article are to assess the completeness of the data collected on site-specific factors (SSFs) as a part of Collaborative Stage (CS) version 2 and the impact of the transition from the American Joint Committee on Cancer's (AJCC) 6th to 7th edition guidelines on stage distribution.METHODSIncidence data for melanomas of the skin from 18 Surveillance, Epidemiology, and End Results (SEER) registries (SEER-18) were analyzed. Percentages of unknown cases for 7 SSFs were examined, along with staging trends from 2004 to 2010 and differences in AJCC 6th and 7th edition stage distributions for 2010 cases.RESULTSFewer than 10% of cases were coded as unknown for SSFs 1 (measured thickness), 2 (ulceration), and 3 (lymph node metastasis). For the remaining SSFs, 36-81% of cases were coded as unknown. Stage distributions were relatively consistent across time and between the AJCC 6th and 7th editions, with the exception of stage IA and stage INOS (not otherwise specified), for which a shift in cases was observed between the AJCC 6th and 7th edition guidelines fOR 2010 cases.CONCLUSIONSA shift of cases out of stage IA and into stage INOS was observed between the AJCC 6th and 7th edition guidelines for 2010 cases. This was attributed to the high number of cases coded as unknown for SSF7 (primary tumor mitotic count/rate). The percentage of cases coded as unknown varied by SSF. Data completeness presents an issue for SSFs introduced in CS version 2. Cancer 2014;120(23 suppl):3807-14. (c) 2014 American Cancer Society.This report highlights the changes in Collaborative Stage for melanomas of the skin as TNM moved from the AJCC 6th to the 7th edition. Stage distributions were relatively consistent across time and between the AJCC 6th and 7th editions, with the exception of stage IA, for whichbecause of the addition of mitotic rate in the assignment of stage IA in the 7th edition and the large number of cases missing this informationa shift into stage INOS was observed.