Community-based study on elderly CKD subjects and the associated risk factors
Community-based study on elderly CKD subjects and the associated risk factors
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DOI：
10.1080/0886022x.2016.1229987
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发表时间：
2016-11-01
期刊：
影响因子：
3
通讯作者：
Mao, Pei-Jv
中科院分区：
文献类型：
--
作者：
Huang, Yan-Ping;Zheng, Tao;Mao, Pei-Jv
目的：为了解上海市社区老年人群慢性肾脏病（CKD）的患病情况及危险因素，为CKD的早期诊断和治疗提供依据，提高老年人的生活质量。他们接受了采访，并通过CKD-EPI方程估计GFR的肾功能下降进行了测试。人口统计学特征、健康特征（例如，结果：约16.4%的参与者患有CKD。平均年龄74.97.0岁。女性CKD患病率显著高于男性（17.6% vs. 14.9%）。CKD患者女性、高尿酸血症（29.6% vs. 18.7%）、高血压（45.1% vs. 40.3%）和心血管疾病（23.2% vs. 18.7%）的患病率高于非CKD人群。CKD患者饮酒率低于非CKD人群。女性CKD患病率是男性的2.002倍。CKD患病率随年龄的增加而增加，每增加1岁患病率增加1.048倍。CKD的危险因素为年龄、女性、高尿酸血症、心血管疾病、高血压、高胆固醇血症、吸烟。结论：上海市老年人群CKD患病率高于成人。老年CKD患者的大多数风险因素与成人人群相似。但高胆固醇血症作为老年CKD的危险因素与成人CKD不同。
Objective: To investigate the prevalence and risk factors for chronic kidney disease (CKD) among community elderly population in Shanghai, China, in order to provide early diagnosis and treatment of CKD, and improve the quality of life for elderly people.Methods: In all, 24,886 residents (65 years old) were selected from community population in Changning District of Shanghai, China in 2014. They were interviewed and tested for reduced renal function estimated GFR by CKD-EPI equation. The associations among demographic characteristics, healthy characteristics (e.g., cardiovascular disease and hypertension), and indicators of kidney damage were examined.Results: Approximately, 16.4% of the participants were CKD. The average of them was 74.97.0 years old. Females had a significantly higher prevalence of CKD than males (17.6% vs. 14.9%). CKD patients were present in higher prevalence of female, hyperuricemia (29.6% vs. 18.7%), hypertension (45.1% vs. 40.3%), and cardiovascular disease (23.2% vs. 18.7%) than that of non-CKD population. CKD patients were present in lower prevalence of drinking than that of non-CKD population. The prevalence of CKD in female is 2.002 times than that of male. The prevalence of CKD increased 1.048 times with the age of each increase in 1 year old. The risk factors for CKD are age, female, hyperuricemia, cardiovascular disease, hypertension, hypercholesterolemia, and smoking.Conclusions: The prevalence of CKD is high in the elderly population than that of adult CKD in Shanghai. The most risk factors for elderly CKD patients are similar to the adult population. But hypercholesterolemia as a risk fact of elderly CKD is different from adult CKD.