Asthma in rural Bangladeshi children
Asthma in rural Bangladeshi children
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DOI：
10.1007/s12098-007-0104-0
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发表时间：
2007-06-01
影响因子：
4.3
通讯作者：
Iwata, Tsutomu
中科院分区：
文献类型：
--
作者：
Zaman, Khalequz;Takeuchi, Haruko;Iwata, Tsutomu
Objective.虽然支气管哮喘在孟加拉国儿童中造成了大量的发病率，但很少有流行病学研究涉及这一问题。本研究旨在确定喘息的患病率及其与环境和宿主因素的关系。共有1587名60-71个月的儿童生活在50个村庄，在孟加拉国农村在Matlab进行了研究。经过培训的现场工作人员采访了这些儿童的照顾者，使用国际儿童哮喘和过敏研究（ISAAC）的调查问卷诊断喘息。从监测记录中获得儿童期喘息和非喘息儿童的肺炎史。调查前最后12个月内喘息的患病率为16.1%（95% CI：14.3%，18.0%），婴儿期有肺炎发作的儿童显著高于无肺炎发作的儿童（23.0% vs 14.6%，p < 0.0001）。与喘息相关的危险因素是0- 12岁儿童的肺炎（OR= 1.50，95%CI 1.08，2.10）和13- 24个月（OR= 2.12，1.46，3.08），母亲哮喘（OR= 3.01，95%CI 2.02，4.47）、父亲哮喘（OR= 3.12，95%CI 1.85，5.26）、母亲湿疹（OR= 1.81，95%CI 1.14，2.87）和家庭收入
Objective. Although bronchial asthma causes a great deal of morbidity among children in Bangladesh, few epidemiological studies addressed this problem. The study aims to determine the prevalence of wheezing and its association with environmental and host factors.Methods. A total of 1587 children aged 60-71 mth living in 50 villages in rural Bangladesh at Matlab was studied. Trained field workers interviewed caretakers of these children to diagnose wheezing using an adopted questionnaire of the International Studies of Asthma and Allergies in Childhood (ISAAC). History of pneumonia among wheezing and non-wheezing children during their childhood was obtained from the surveillance records.Results. The prevalence of wheezing in the last 12 mth prior to survey was 16.1% (95% Cl: 14.3%, 18.0%), significantly higher among children who had attacks of pneumonia during their infancy compared to children who did not (23.0% vs 14.6%, p < 0.0001). Risk factors associated with wheezing were pneumonia at ages 0-12m (OR= 1.50, 95% Cl 1.08, 2.10) and 13-24m (OR= 2.12, 1.46, 3.08), maternal asthma ( OR= 3.01, 95% Cl 2.02, 4.47), paternal asthma (OR= 3.12, 95% Cl 1.85, 5.26), maternal eczema (OR= 1.81, 95% Cl 1.14, 2.87) and family income