Bone mineralization in the first year of life in infants fed human milk, cow-milk formula, or soy-based formula.

Bone mineralization in the first year of life in infants fed human milk, cow-milk formula, or soy-based formula.
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喂养母乳、牛奶配方奶粉或大豆配方奶粉的婴儿第一年的骨矿化情况。

DOI:
10.1016/s0022-3476(05)83415-8
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发表时间:
1993
期刊:
The Journal of pediatrics
影响因子:
--
通讯作者:
Tsang,RC
Tsang,RC
中科院分区:
--
文献类型:
--
作者:
Mimouni,F;Campaigne,B;Neylan,M;Tsang,RC

文献摘要

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目的检验以下假设:(1)喂养大豆配方奶粉(SBF)和人乳(HM)的婴儿骨矿物质含量(BMC)相似,喂养牛奶配方奶粉(CBF)的婴儿更高,(2)喂养配方奶粉的婴儿和喂养人乳的婴儿血清1,25-二羟维生素D(矿物质充足的指标)相似。72个婴儿:10例给予HM,20例给予CBF(Similac),21例给予SBF(Isomii),21例给予SBF(Prosobee)。测量:基线(生命的第2天至第7天)和8、16、26和52周龄时的BMC和1,25-二羟维生素D水平。BMC是相似的各组在所有时间;血清1,25-二羟维生素D水平相似的各组,除了他们在8,16和26周升高,在那些喂养Prosobee.Conclusions:(1)BMC是相似的SBF,CBF和HM喂养的婴儿和(2)血清1,25-二羟维生素D浓度的代偿性升高可能会发生在SBF喂养的婴儿。
ObjectiveTo test the hypotheses that (1) bone mineral content (BMC) is similar in infants fed soy-based formula (SBF) and human milk (HM) and higher in infants fed cow milk-based formula (CBF) and (2) serum 1,25-dihydroxyvitamin D, an index of mineral sufficiency, is similar in infants fed formula and infants fed HM.Design:Randomized, prospective study of formula-fed group onlySetting:Recruitment was in a normal newborn nursery.Patients: 72 infants: 10 given HM, 20 given CBF (Similac), 21 given SBF (Isomii), and 21 given SBF (Prosobee).Measurements: BMC and 1,25-dihydroxyvitamin D levels at baseline (days 2 through 7 of life) and at 8, 16, 26, and 52 weeks of age. The BMC was similar in all groups at all times; serum 1,25-dihydroxyvitamin D levels were similar in all groups, except that they were elevated at 8, 16, and 26 weeks in those fed Prosobee.Conclusions: (1) BMC is similar in SBF-, CBF, and HM-fed infants and (2) compensatory elevation of serum 1,25-dihydroxyvitamin D concentrations may occur in SBF-fed infants.