Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic
Epidemiology, transmission dynamics and control of SARS: the 2002-2003 epidemic
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DOI：
10.1098/rstb.2004.1490
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发表时间：
2004-07-29
影响因子：
6.3
通讯作者：
Hedley, AJ
中科院分区：
文献类型：
--
作者：
Anderson, RM;Fraser, C;Hedley, AJ
本文综述了严重急性呼吸综合征（SARS）的流行病学、传播动力学和控制方面的研究进展。我们目前的数据分析的关键参数和分布，并讨论了数据采集，分析和公共卫生政策的制定过程中，SARS疫情进行了讨论。病毒的低传染性，加上疾病临床症状出现后传染性高峰期的出现，使得简单的公共卫生措施，如隔离患者和排除其接触者，在控制SARS流行方面非常有效。我们的结论是，这一次我们是幸运的，但下一次新病原体的流行病爆发可能就不是这样了。我们提出的分析，有助于进一步了解什么样的干预措施可能是最好的工作与定义的生物和流行病学特性的传染性病原体。这些从SARS经验中吸取的教训是在流行病学和公共卫生背景下提出的。
This paper reviews current understanding of the epidemiology, transmission dynamics and control of the aetiological agent of severe acute respiratory syndrome (SARS). We present analyses of data on key parameters and distributions and discuss the processes of data capture, analysis and public health policy formulation during the SARS epidemic are discussed. The low transmissibility of the virus, combined with the onset of peak infectiousness following the onset of clinical symptoms of disease, transpired to make simple public health measures, such as isolating patients and quarantining their contacts, very effective in the control of the SARS epidemic. We conclude that we were lucky this time round, but may not be so with the next epidemic outbreak of a novel aetiological agent. We present analyses that help to further understanding of what intervention measures are likely to work best with infectious agents of defined biological and epidemiological properties. These lessons learnt from the SARS experience are presented in an epidemiological and public health context.