Gene therapy and transplantation.
Gene therapy and transplantation.
复制标题
基因治疗和移植。
DOI:
10.1097/00007890-200005270-00001
复制
发表时间:
2000
期刊:
影响因子:
6.2
通讯作者:
LeGuern,C
中科院分区:
文献类型:
--
作者:
Gojo,S;Cooper,DK;Iacomini,J;LeGuern,C
Advances in molecular biology and in techniques of gene transfer have resulted in the development of practical approaches to human gene therapy. Many applications are of relevance to manipulation of the immune system and have potential in organ and cell transplantation. For example, gene therapy approaches may facilitate the induction of immunological tolerance to a donor organ or protect it locally against the host’s immune response. Based on a comprehensive review of the world literature, examples of current research efforts in both allogeneic and xenogeneic transplantation are presented and discussed.